Low blood uric acid levels are observed in neurological diseases such as Alzheimer’s disease, Parkinson’s disease, ALS, multiple sclerosis, schizophrenia, and central nervous system viral infections. High blood uric acid levels are observed in hypertension, type II diabetes, chronic kidney disease, heart disease, and non-alcoholic fatty liver disease. Poor kidney clearance of uric acid can result in uric acid accumulation in joints which causes gout.
To access the FREE seminars with full presentations and videos please visit Dr. Goodenowe’s resource site here. This is the article for seminar B112, Blood Tests and Biomarkers (Series B).
Uric acid is a waste by-product of purine metabolism. Purines are heterocyclic bases that are used in many biochemical processes. For example, the adenosine in adenosine triphosphate (ATP) is a purine. Several of the bases that make up DNA and RNA are purines. Meat and beer contain purines. Clinical studies that investigated the relationship between blood uric acid levels and all-cause mortality reveal that either higher than or lower than normal levels are associated with an increased risk of mortality.
Dr. Goodenowe explains the relevant research and literature regarding blood uric acid levels in seminar B112 – Uric Acid.