Month: December 2021

Lecture 11 – Biochemistry of Plasmalogen Supplementation

When it became clear that several serious, mortal, and mostly untreatable rare diseases were due to defects in peroxisomes and that plasmalogen deficiency alone is sufficient to cause mortality and morbidity in these diseases, research into the biochemical pathways necessary for the biosynthesis of plasmalogens was intensified. The peroxisomal biosynthesis of plasmalogens was (and still is) believed to end at the formation of the alkyl ether bond and …

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Lecture 10 – Plasmalogens and the Epidemiology of Alzheimer’s Dementia

Plasmalogens were first discovered in 1924, almost 100 years ago. Peroxisomes, the intracellular organelle where plasmalogens are made, were discovered in 1960. The rare cerebrohepatorenal syndrome called Zellweger’ syndrome was first identified in the mid 1960’s. This is a very serious disease. Children with this disease typically die within 6 months of birth. In 1973 it was discovered that Zellweger’ syndrome was caused by a lack of peroxisomes. In 1979 it …

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Lectures 9, 10, and 11 of Breaking Alzheimer’s – The Definitive Lecture Series launched today

Dr. Dayan Goodenowe created Breaking Alzheimer’s: The Definitive Lecture Series as a detailed scientific treatise to continue the awakening process that he began in Breaking Alzheimer’s – The Book. The Definitive Lecture Series is designed to provide a full and complete understanding of the key aspects of brain health changes that are associated with Alzheimer’s disease and cognition. In …

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Lecture 9 – The Biochemistry of Oxidative Stress: Breaking Alzheimer’s

The terms “Oxidative Stress” and “Reactive Oxygen Species” are commonly bandied about as is the term “Anti-Oxidant”. What do these terms really mean? Where does oxidative stress come from? How does the human body create and regulate reactive oxygen species? What happens when your body’s anti-oxidation mechanisms become overwhelmed?   Join Dr. Goodenowe for Lecture 9 – The Biochemistry of Oxidative Stress and find the answers to these questions and …

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