Uric Acid (B112)

Low blood uric acid levels are observed in neurological diseases such as Alzheimer’s disease, Parkinson’s disease, ALS, multiple sclerosis, schizophrenia, and central nervous system viral infections. High blood uric acid levels are observed in hypertension, type II diabetes, chronic kidney disease, heart disease, and non-alcoholic fatty liver disease. Poor kidney clearance of uric acid can result in uric …

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Creatinine and Blood Urea Nitrogen (B111)

Low blood creatinine is associated with liver dysfunction, muscle wasting, and sarcopenia whereas high blood creatinine is associated with kidney disease.  Creatinine is a metabolic product of creatine phosphate which is the main energy source for muscles. Typically, due to higher overall muscle mass, men have naturally higher levels of creatine phosphate. Creatine, the metabolic precursor of creatine phosphate is not made in muscles but …

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Total, HDL, and LDL Cholesterol (B110)

Maintaining healthy circulating cholesterol levels is essential for optimal health. Low cholesterol levels are indicative of impaired liver or peripheral cell health and is associated with increased mortality.  To access the FREE seminars with full presentations and videos please visit Dr. Goodenowe’s resource site here. This is the article for seminar B110, Blood Tests and Biomarkers (Series B). Cholesterol …

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Fasting Triglycerides and Peroxisomal Function (B109)

Maintaining low fasting triglycerides is essential to optimal health. High fasting triglycerides are indicative of mitochondrial or peroxisomal impairment, the two organelles responsible for fatty acid metabolism in our cells.  To access the FREE seminars with full presentations and videos please visit Dr. Goodenowe’s resource site here. This is the article for seminar B109, Blood Tests and Biomarkers …

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Fatty Acid Elongase (B108)

Women diagnosed with active breast cancer or ovarian cancer have elevated fatty acid elongase activity. Abnormal cell growth (i.e., cancer) results in the activation of certain elongase enzymes which are used to make the long-chain polyunsaturated fatty acids required to populate the sn-2 position of membrane phospholipids. The predominate fatty acid synthetized is arachidonic acid (20:4), which is made from the essential dietary omega-6 fatty …

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High Sensitivity C-Reactive Protein (B107)

C-Reactive Protein (CRP) is a non-specific biomarker of systemic inflammation. High blood CRP levels are associated with numerous diseases and increased risk of all-cause mortality and disease-specific mortalities. There are multiple potential inflammation cascades that contribute to elevated CRP.   To access the FREE seminars with full presentations and videos please visit Dr. Goodenowe’s resource site here. This is the article for …

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Mitochondrial Stress and Leakage (B106)

Mitochondria are the most important organelle in the human body. Life cannot exist without functioning mitochondria. The key function of the mitochondria is to convert the stored chemical energy of hydrocarbons into the biochemically useful energy of ATP. All carbon-based life is based upon the conversion of sunlight energy into hydrocarbon energy by combining carbon dioxide (CO2) and water (H2O) …

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Homocysteine and Methyltransferase Capacity (B105)

High homocysteine levels are associated with an increased risk of dementia, metabolic syndrome, and all-cause mortality. Homocysteine is a biomarker of methyltransferase activity and function.  To access the FREE seminars with full presentations and videos please visit Dr. Goodenowe’s resource site here. This is the article for seminar B105, Blood Tests and Biomarkers (Series B). The methyltransferase system is a critical nexus for multiple …

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Total Iron (B104)

Approximately 30% of the population are mildly anemic. Optimal iron levels are associated with healthy mitochondrial and peroxisomal function as well as a decreased risk of cancer. All biochemical processes that use molecular oxygen such as mitochondrial and peroxisomal fatty acid β-oxidation, the mitochondria electron transport chain, transportation of oxygen in the blood via hemoglobin, etc. all …

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Gastrointestinal Tract Acids (GTAs) (B103)

Persons deficient in GTAs have been shown to have an increased risk of colorectal cancer and pancreatic cancer and other inflammatory diseases. GTAs are ultra-long chain fatty acids that are made by gut microbes and absorbed into the blood supply. They have anti-inflammatory and anti-cancer properties. Over 90% of colorectal and pancreatic cancer cases are detected in …

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